WebJul 20, 2024 · Immunoassay interference: Biotin taken in moderate to high doses can result in either false-high or -low values . Clinically significant lab errors: In a 67-year-old female with a history of multiple endocrine issues following biotin supplementation. WebApr 25, 2024 · The concentration of biotin at which biotin interference is seen varies between immunoassays. For some immunoassays, interference can occur at biotin concentrations as low as 10 ng/mL (40.9 nmol/L – to convert ng/mL to nmol/L, multiply by 4.09). 2 For other immunoassays, interference may only occur at concentrations of 200 …
Testing for Biotin Interference in In Vitro Diagnostic …
WebMay 1, 2024 · Biotin interference is a relatively new discovery , but many of the methods used to investigate this interference overlap with those that are classically recognized. … WebNov 26, 2024 · Background Biotin is currently a matter of concern for laboratories using biotin-streptavidin-based immunoassays. Biotin interferences have been reported for high-sensitive troponin T (hsTnT) and thyroid-stimulating hormone (TSH) assays. We aimed to evaluate the new generation of hsTnT and TSH elect … north charleston redistricting
Biotin Interference in Diagnostic Tests Clinical Chemistry Oxford ...
WebAs the FDA reported in a safety communication in 2024, the agency is aware of people taking high levels of biotin that may cause interference with lab tests. Many diagnostic tests use biotin ... WebMay 18, 2024 · (2024, May 18). Biotin supplements caused misleading test results, almost led to unnecessary procedure: FDA issued warning about biotin interference with lab … WebMar 6, 2024 · Yes. On November 28, 2024, the FDA issued a safety communication indicating that biotin in specimens from people taking biotin supplements may cause interference with some laboratory assays. 3 The warning stated, “The FDA is alerting the public, health care providers, lab personnel, and lab test developers that biotin can … how to reset my ring