C4hc3-type e3 ligase
WebTherefore, these results establish unambiguously that the K3 C4HC3-type domain (and by inference those of the entire related viral and human families) is a variant type of RING domain. Identification of K3-interacting Ubiquitin-conjugating Enzymes— In order to function as an E3 ubiquitin-protein ligase, a protein must interact with at least ... WebThe Evolutionarily Conserved E3 Ubiquitin Ligase AtCHIP Contributes to Plant Immunity. Charles Copeland 1,2†, Kevin Ao 1,2†, Yan Huang 1,2, Meixuizi Tong 1,2 and Xin Li 1,2*. 1 Michael Smith Laboratories, …
C4hc3-type e3 ligase
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WebK3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain* Received for publication, August 23, 2004, and in revised form, September 28, 2004 ... the E3 ubiquitin-protein ligase, which possesses a substrate recognition module, acts to bridge E2 and the target, allowing formation of isopep-tide bonds between target lysine -amino ...
WebE3 ligase activity toward selected targets,14 and it also facilitates nuclear retention of the protein.13,15,16 The SP-RING domain is required for E3 ligase activity.16,17 The PHD domain of SIZ1, a C4HC3 zinc fin-ger, functions as a SUMO E3 ligase for selected targets such as bromodomain-containing proteins.18 The PHD domain WebMar 3, 2024 · The membrane-associated RING-CH-type finger (MARCHF) proteins are a subfamily of the RING-type E3 ubiquitin ligase family . The MARCHF proteins contain a C4HC3-type RING domain, initially identified in K3 and K5 ubiquitin ligases of Kaposi’s sarcoma-associated herpesvirus (KSHV) [ 17 – 19 ].
WebOne-sentence summary: A microtubule-associated E3 ligase ubiquitinates and promotes degradation of a serine hydroxymethyltrasferase, resulting in broad-spectrum resistance to … WebJun 1, 2024 · This study signifies the putative role of RING-type E3 ligases in amylose biosynthesis and this information will be helpful for further functional validation and its …
WebJan 11, 2005 · With more than 1,300 genes predicted to encode for E3 components, ubiquitin ligases account for the majority of the proteins involved in the ubiquitnation/26S …
WebFeb 6, 2007 · E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation (PubMed:15673284). Promotes ubiquitination of DIO2, leading to its degradation (PubMed:19651899). Promotes ubiquitination of SQLE, leading to its degradation (PubMed:24449766). E3 ubiquitin … ghum kisi pyar mein watch onlineWebJul 24, 2024 · Membrane-associated RING-CH-type finger (MARCH) proteins are a subfamily of the RING-type E3 ubiquitin ligases ( 2 ). MARCH proteins contain a C4HC3 … frosted safety glass panelWebJul 1, 2024 · For example, the HECT type E3 ubiquitin ligase,the ortholog of Arabidopsis UBIQUITIN PROTEIN LIGASE3 (UPL3),BnaUPL3 C03 in B. napus negatively affects the seed weight per pod by mediating the degradation of LEAFY COTYLEDON2 (LEC2), which is a master transcriptional regulator of seed maturation [10]. ghumkuria is found in which tribeWebFeb 24, 2024 · Fu et al. (2024) moved to connect viral defenses to other biotic levels by identifying an interaction between MEL, a microtubule-associated C4HC3-type E3 … ghumman impex limitedWebJan 1, 2014 · The PHD/LAP finger found in the transcription factor NF-X1 and the MARCH family of membrane-bound E3s is defined by its C4HC3 consensus. RINGs having a C8 configuration (CNOT4) ... In contrast to HECT-type E3 ligases, RING-type E3s lack a bona fide catalytic center. A lingering question in the field has been whether RINGs serve … frosted seed beadsWebAug 16, 2012 · Here, we identified the E3 ubiquitin ligase membrane-associated RING-CH (MARCH8) as a suppressor of IL-1β–induced NF-κB- and MAPK-activation pathways. … ghumman and partnersWebFeb 12, 2013 · The SUD1 Gene Encodes a Putative E3 Ubiquitin Ligase and Is a Positive Regulator of 3-Hydroxy-3-Methylglutaryl ... Chemical analysis indicated that the dry2/sqe1-5 mutant has altered sterol composition in roots but wild-type sterol composition ... domain (C4HC3 RING-finger domain) near the N terminus (Stone et al., 2005; Lü et al., 2012 ... frosted screens